New Preprint!

In our most recent study, we developed a novel panoramic optical mapping system with which it is possible to image action potential waves across the entire surface of contracting isolated hearts. The imaging system consists of 12 high-speed cameras positioned around the heart, which is imaged inside a soccer ball-shaped imaging chamber. We demonstrate that it is possible to measure action potential waves together with tissue mechanics during sinus rhythm, paced rhythm and ventricular fibrillation on the entire contracting ventricular surface. In the future, we will employ up to 24 high-speed cameras for the imaging of voltage and calcium waves. The imaging system is described in a preprint available on arXiv (Link). Congratulations to Shrey Chowdhary, Jan Lebert and Shai Dickman, who made this happen!